PATRICIA Y. SCARAFFIA, Ph.D.

Research Assistant Professor

Dept. of Chemistry and Biochemistry
1305 E. 4th Street, Room 234

University of Arizona
Tucson, AZ 85721

scaraffi@email.arizona.edu
Tel: (520) 621-2628
Fax: (520) 621-8407

RESEARCH INTEREST

Nitrogen and carbon metabolism in Aedes aegypti mosquitoes

SELECTED PUBLICATIONS

Jiang W, Wysocki VH, Dodds ED, Miesfeld RL, Scaraffia PY. (2010). “Differentiation and quantification of C1 and C2 13C-labeled glucose by tandem mass spectrometry”. Anal Biochem. 404:40-44.

 

Scaraffia PY, Zhang Q, Thorson K, Wysocki VH, Miesfeld RL (2010). “Differential ammonia metabolism in Aedes aegypti fat body and midgut tissues”. J. Insect Physiol. 56:1040-1049.

 

Scaraffia PY, Tan G, Isoe J, Wysocki VH, Wells MA, Miesfeld RL (2008). “Discovery of an alternate metabolic pathway for urea synthesis in adult Aedes aegypti mosquitoes” Proc. Nat. Acad. Sci USA. 105: 518-523.

Scaraffia PY, Zhang Q, Wysocki VH, Isoe J, Wells MA (2006) “Analysis of whole body ammonia metabolism in Aedes aegypti using [¹⁵N]-labeled compounds and mass spectrometry” Insect Biochem Mol Biol, 36: 614-622.

Zhang Q,Wysocki VH, Scaraffia PY, Wells MA (2005) “Fragmentation Pathway for Glutamine Identification: Loss of 73 Da from Dimethylformamidene Isobutyl Glutamine” J Am Soc Mass Spectrom, 16:1192-1203.

Scaraffia PY, Isoe J, Murillo A, Wells MA (2005) “Ammonia metabolism in Aedes aegypti.” Insect Biochem Mol Biol. 35: 491-503.

Zhou G, Scaraffia PY, Wells MA (2005) “Vector nutrition and energy metabolism”. In: Marquardt, W.C., Black, W.C., Freier, J.E., Hagedorn, H.H., Hemingway, J., Higgs, S., James, A.A., Kondratieff, B., Moore, C.G. (Eds.), 2nd ed. Biology of Disease Vectors. Elsevier Academic press, London, pp. 211-315.

Scaraffia PY, Wells MA (2003) “Proline can be utilized as an energy substrate during flight of Aedes aegypti females”. J. Insect Physiol 49:591-601.

Scaraffia PY, Maldonado C, Aoki A, Gerez de Burgos NM (2001) “Comparative study of enzymes in testes and ovaries from Dipetalogaster maximus (Uhler) and Triatoma infestans (Klug) (Hemiptera: Reduviidae).Correlation with fine structural organization” Eur. J. Histochem. 45:295-303.

Cavagnari B, Scaraffia PY, Haller JF, Gerez de Burgos NM, Santome JA (2000). “Presence of fatty acid-binding protein and lipid stores in flight muscles of Dipetalogaster maximus (Hemiptera: Reduviidae)”. J. Med. Entomol. 37: 938-944.

Scaraffia PY, Gerez de Burgos, NM (2000).“Effects of temperature and pH on Hexokinase from flight muscles of Dipetalogaster maximus (Hemiptera: Reduviidae). J. Med. Entomol 37 :689-694.

Scaraffia PY, Remedi MS, Maldonado C, Aoki A, Gerez de Burgos NM (1999). “Thoracic muscles of Triatomine insects: Biochemical adaptations for flight activity”. In:  Carcavallo, R. U., Giron, I.G., Jurberg, J., Lent, H. (Eds.), Atlas of Chagas disease vectors in America. Ed Fiocruz. Río de Janeiro. Brazil, pp 1105-1113.

Scaraffia PY, Remedi MS, Maldonado C,  Aoki A and Gerez de Burgos NM (1997). “Enzymatic and ultrastructural changes in thoracic muscles of triatomine insects during the last stage of metamorphosis”. Comp. Biochem. Physiol. 116: 173-179.